Human Disease Modifier Genes
Diversity between patients who suffer from the same disease promote studies that focus on the surrounding aspects. The aim of these research branches is to study the genetic and biomolecular aspects of certain diseases, including genetic predisposition, clinical diagnosis and the identification of new therapeutic targets. BIOMICs UPV/EHU focuses on modifier genes that impact on the diagnosis and treatment of certain illnesses.
Cystic Fibrosis
SARS-CoV-2
Publications (last 10 years):
1. Kleinbielen T, Palencia-Madrid L, Garcia-Ibarbia C, Ortiz F, Riancho JA, M de Pancorbo M. Association of LCT -13910C>T polymorphism and hip fracture in a cohort of older adult population from Northern Spain. Gene. 2021. 30;783:145560. doi: 10.1016/j.gene.2021.145560
2. Kleinbielen T, Hernández-Sierra MP, Prieto-Fernández E, Olasagasti F, Sevillano R, M De Pancorbo M. NOS1AP SNPs related to sudden arrhythmic death syndrome. Forensic Science International: Genetics Supplement Series. 2019. 7(1);569-571. doi.org/10.1016/j.fsigss.2019.10.093.
Congress contributions (last 10 years):
45th European Cystic Fibrosis Conference - Rotterdam, the Netherlands, 2022
Granizo-Rodríguez E. , Baeta M., Kleinbielen T., Padura O., Arizti P., Baranda F. and de Pancorbo M.M. E-Poster and Oral Presentation: “Cystic fibrosis modifier genes and bacterial infections in spanish patients”.
28th Congress of the International Society for Forensic Genetics (ISFG) – Prague, Czech Republic, 2019C
Tamara Kleinbielen, María del Pilar Hernández Sierra, Endika Prieto-Fernández, Felix Olasagasti, Rubén Sevillano, Marian M. De Pancorbo. Poster presentation: “Study of biomarkers related to Sudden Arrhythmic Death Syndrome”.