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Our Group

 

BIOMICs is a multipidisciplinar Research Group in the University of the Basque Country that develops its research in biosciences and microtechnologies at the Lascaray Research Center in the Campus of Araba in Vitoria-Gasteiz.


​The team of BIOMICs bioscience area is formed by one full professor, one titular professor, 1 aggregated professor,  three Ph.D. researchers, four predoctoral researchers and several master students.

News&Events

February 2019

  • Teknopolis Award

Prof. Dr. Marian M. de Pancorbo received the H2  award one of the ten prizes awarded by twenty anniversary of Teknopolis from Elhuyar Foundation.

April 2019

Ms. VILLAESCUSA, PhD student from the BIOMICs Research Group, defended with summa cum laude her thesis entitled "New insights in the paternal genetic landscape of Southwestern Europe: dissection of haplogroup r1b-m269 and forensic applications".

June 2018

  • Extraordinary Doctorate Award 

PhD Dr. Endika Prieto has received the Extraordinary Doctorate Award in Experimental Sciences, University of the Basque Country UPV/EHU. Congratulations Endika!!!

November 2017

  • VI Edition of the ASEBIO Award for Communication and Dissemination of Biotechnology

Prof. Dr. Marian M. de Pancorbo has participated in the  the report “CRISPR / Cas9, the genetic cutter” awarded by ASEBIO in the Television and Radio category.

 

November 2017

  • THE BEST YOUNG RESEARCHER AWARD 

PhD Dr. Miriam Baeta has received the Best Young Researcher Award 2017. She works as a post-doctoral researcher in the research group of BIOMICs. The prize was given at the XVIII Research Conference organized by the OSI Araba and the Álava Campus of the UPV / EHU. which was held in Vitoria-Gasteiz(Sapain) 8-9th November 2017. 

May 2017

Mr. PRIETO-FERNÁNDEZ, PhD student from the BIOMICs Research Group, defended with summa cum laude his thesis entitled "X-CHROMOSOME MARKERS IN FORENSIC GENETICS: Evaluation and development of a new 17 X-STR multiplex reaction".

 

December 2016

Ms. Gil Arriortua, PhD student from the BIOMICs Research Group, defended with summa cum laude her thesis entitled "Entomología molecular: Diversidad y filogenia de dípteros de interés médico-legal y veterinario, y su
aplicación en situaciones reales” supervised by Dr. Marian M. de Pancorbo and Dr. Marta I. Saloña. Congratulations Dr. Gil Arriortua!

November 2016

M. López-Oceja, PhD student from the BIOMICs Research Group, defended with summa cum laude his thesis entitled "ADNmt: caracterización de razas bovinas y ovinas autóctonas del país vasco e identificación de especies animales de interés económico y forense” supervised by Dr. Marian M. de Pancorbo. Congratulations Dr. López-Oceja!

 

October 2016

  • THE BEST YOUNG RESEARCHER AWARD 

PhD Dr. Carolina Nuñez has received the Best Young Researcher Award 2016. She works as a post-doctoral researcher in the research group of BIOMICs. The prize was given at the XVII Research Conference organized by the OSI Araba and the Álava Campus of the UPV / EHU. which was held in Vitoria-Gasteiz(Sapain) 19th October 2016. Congratulations Carol!!!

October 2016

  • THE BEST INTERNATIONAL PUBLICATION 

The article "Tunable Nanoparticle and Cell Assembly Using Combined Self-Powered Microfluidics and Microcontact Printing" led by the researcher Lourdes Basabe Desmonts (BIOMICs Research Group), received the first prize in the category "best international publication" presented at the XVII Research Conference organized by the OSI Araba and the Álava Campus of the UPV / EHU. Congratulations Lourdes!!!

October 2016

The method of detecting chimerism routinely used is the STRs. Recently, the European SNPforID group has validated a panel of multiple minesequencing by SNaPshot® of 52 autosomal SNPs whose ability to discriminate between individuals could be very useful for the follow-up of transplants of allogeneic bone marrow transplants.Tamara, during her master's degree work, has demonstrated the utility of this multiple minisequencing panel to the follow-up of allogeneic bone marrow transplant recipients. Great job Tamara !!!

October 2016 - February 2017

  • MASTER ON FORENSIC ANALYSIS 

Marian, Carol, Miriam and Leire from the BIOMICS Group will deliver courses on Forensic Genetics.

If you are interested in the Master on Forensic Analysis of the UPV / EHU go to ttps://www.ehu.eus/es/web/masteranalisisforense/aurkezpena and http://www.biomics.es/158211691

September 2016

  • GRADUATION OF OUR MASTER STUDENTS

Congratulations to Tamara Soledad Kleinbielen, Ana Díaz, Cristina Perez Aguado, Diana Vinueza, Miguel Guerra and Jaione Jauregui for their Master Thesis defenses.

 

 

 

 

 

 

 

 

 

 

 

 

Site Title

Forensic Genetic Services

 

  • Kinship analyses

  • Ancestrality

  • Human remains identification

  • Archaeological remains

Biomedicine

  • Lactose intolerance

Microtechnologies

Education and outreach

Papers recently published


A great work of the Group and in particular of the first authors who have been Miriam Baeta, Endika Prieto-Fernandez, Andrés López-Oceja, Carolina Núñez, Patricia Villaescusa and Leire Palencia
 

We list below the articles, as well as the DOI and PMID.

  • 1: Palencia-Madrid L, Sánchez-Valle R, Fernández de Retana I, Borrego S, Grau-Rivera O, Reñé R, Hernández I, Almenar C, Rossi G, Caroppo P, Redaelli V, Le Ber I, Camuzat A, Brice A, Antonell A, Balasa M, Gelpi E, Lladó A, de Pancorbo MM. A unique common ancestor introduced P301L mutation in MAPT gene in frontotemporal dementia patients from Barcelona (Baix Llobregat, Spain). Neurobiol Aging. 2019 Aug 21. pii: S0197-4580(19)30293-3. doi: 10.1016/j.neurobiolaging.2019.08.015. [Epub ahead of print] PubMed PMID: 31537395.

  • 2: Palencia-Madrid L, Baeta M, Villaescusa P, Nuñez C, de Pancorbo MM, Luis JR, Fadhlaoui-Zid K, Somarelli J, Garcia-Bertrand R, Herrera RJ. The Marquesans at the fringes of the Austronesian expansion. Eur J Hum Genet. 2019 May;27(5):801-810. doi: 10.1038/s41431-019-0336-2. Epub 2019 Jan 25. PubMed PMID: 30683925; PubMed Central PMCID: PMC6461844.

  • 3: Palencia-Madrid L, Cardoso S, Castro-Maestre F, Baroja-Careaga I, Rocandio AM, de Pancorbo MM. Development of a new screening method to determine the main 52 mitochondrial haplogroups through a single minisequencing reaction. Mitochondrion. 2019 Mar;45:46-51. doi: 10.1016/j.mito.2018.02.004. Epub 2018 Feb  21. PubMed PMID: 29474835.

  • 4: Moreno-Grau S, de Rojas I, Hernández I, Quintela I, Montrreal L, Alegret M, Hernández-Olasagarre B, Madrid L, González-Perez A, Maroñas O, Rosende-Roca M, Mauleón A, Vargas L, Lafuente A, Abdelnour C, Rodríguez-Gómez O, Gil S, Santos-Santos MÁ, Espinosa A, Ortega G, Sanabria Á, Pérez-Cordón A, Cañabate P, Moreno M, Preckler S, Ruiz S, Aguilera N, Pineda JA, Macías J, Alarcón-Martín E,  Sotolongo-Grau O; GR@ACE consortium; DEGESCO consortium; Alzheimer's Disease Neuroimaging Initiative, Marquié M, Monté-Rubio G, Valero S, Benaque A, Clarimón  J, Bullido MJ, García-Ribas G, Pástor P, Sánchez-Juan P, Álvarez V, Piñol-Ripoll  G, García-Alberca JM, Royo JL, Franco E, Mir P, Calero M, Medina M, Rábano A, Ávila J, Antúnez C, Real LM, Orellana A, Carracedo Á, Sáez ME, Tárraga L, Boada M, Ruiz A. Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project. Alzheimers Dement. 2019 Oct;15(10):1333-1347. doi: 10.1016/j.jalz.2019.06.4950. Epub 2019 Aug 28. PubMed  PMID: 31473137.

  • 5: Villaescusa P, Palencia-Madrid L, Campaner MA, Jauregui-Rada J, Guerra-Rodríguez M, Rocandio AM, de Pancorbo MM. Effective resolution of the Y chromosome sublineages of the Iberian haplogroup R1b-DF27 with forensic purposes. Int J Legal Med. 2019 Jan;133(1):17-23. doi: 10.1007/s00414-018-1936-z. Epub 2018 Sep 18. PubMed PMID: 30229332.

  • 6: Messoussi M, Prieto-Fernández E, Baeta M, Núñez C, Gaaied ABA, de Pancorbo MM, Fadhlaoui-Zid K. Genetic variation of 17 X-chromosome STR loci in Tunisian population of Nabeul. Int J Legal Med. 2019 Jan;133(1):85-88. doi: 10.1007/s00414-018-1827-3. Epub 2018 Mar 22. PubMed PMID: 29569161.

  • 7: Carrasco-Garcia E, Moreno-Cugnon L, Garcia I, Borras C, Revuelta M, Izeta A, Lopez-Lluch G, de Pancorbo MM, Vergara I, Vina J, Matheu A. SOX2 expression diminishes with ageing in several tissues in mice and humans. Mech Ageing Dev. 2019 Jan;177:30-36. doi: 10.1016/j.mad.2018.03.008. Epub 2018 Mar 21. PubMed PMID: 29574045.

  • 8: Ruiz B, Aguirre U, Estany-Gestal A, Rodella L, Ruiz P, Figueiras A, Carvajal A, Ibáñez L, Conforti A, de Pancorbo MM, Vidal X, Martin LH, Aguirre C. Only full adherence to proton pump inhibitors protects against drug-induced upper gastrointestinal bleeding. Eur J Clin Pharmacol. 2018 Nov;74(11):1503-1511. doi:  10.1007/s00228-018-2523-4. Epub 2018 Jul 24. PubMed PMID: 30043109.

  • 9: Marqueta-Gracia JJ, Álvarez-Álvarez M, Baeta M, Palencia-Madrid L, Prieto-Fernández E, Ordoñana JR, de Pancorbo MM. Differentially methylated CpG regions analyzed by PCR-high resolution melting for monozygotic twin pair discrimination. Forensic Sci Int Genet. 2018 Nov;37:e1-e5. doi: 10.1016/j.fsigen.2018.08.013. Epub 2018 Sep 21. PubMed PMID: 30245065.

  • 10: Gamarra D, Aldai N, Arakawa A, Barron LJR, López-Oceja A, de Pancorbo MM, Taniguchi M. Distinct correlations between lipogenic gene expression and fatty acid composition of subcutaneous fat among cattle breeds. BMC Vet Res. 2018 May 23;14(1):167. doi: 10.1186/s12917-018-1481-5. PubMed PMID: 29792205; PubMed Central PMCID: PMC5966917.

  • 11: Baeta M, Núñez C, Villaescusa P, Ortueta U, Ibarbia N, Herrera RJ, Blazquez-Caeiro JL, Builes JJ, Jiménez-Moreno S, Martínez-Jarreta B, de Pancorbo  MM. Assessment of a subset of Slowly Mutating Y-STRs for forensic and evolutionary studies. Forensic Sci Int Genet. 2018 May;34:e7-e12. doi: 10.1016/j.fsigen.2018.03.008. Epub 2018 Mar 20. PubMed PMID: 29588179.

  • 12: Prieto-Fernández E, Kleinbielen T, Baeta M, de Pancorbo MM. In-silico evaluation based on public data: In search of forensically efficient tri- and tetrallelic X-SNPs. Forensic Sci Int Genet. 2018 Jan;32:e5-e6. doi: 10.1016/j.fsigen.2017.11.008. Epub 2017 Nov 14. PubMed PMID: 29162489.

  • 13: Lopez-Oceja A, Nuñez C, Baeta M, Gamarra D, de Pancorbo MM. Species identification in meat products: A new screening method based on high resolution  melting analysis of cyt b gene. Food Chem. 2017 Dec 15;237:701-706. doi: 10.1016/j.foodchem.2017.06.004. Epub 2017 Jun 3. PubMed PMID: 28764056.

  • 14: Solé-Morata N, Villaescusa P, García-Fernández C, Font-Porterias N, Illescas  MJ, Valverde L, Tassi F, Ghirotto S, Férec C, Rouault K, Jiménez-Moreno S, Martínez-Jarreta B, Pinheiro MF, Zarrabeitia MT, Carracedo Á, de Pancorbo MM, Calafell F. Analysis of the R1b-DF27 haplogroup shows that a large fraction of Iberian Y-chromosome lineages originated recently in situ. Sci Rep. 2017 Aug 4;7(1):7341. doi: 10.1038/s41598-017-07710-x. PubMed PMID: 28779148; PubMed Central PMCID: PMC5544771.

  • 15: Palencia-Madrid L, Cardoso S, Keyser C, López-Quintana JC, Guenaga-Lizasu A,  de Pancorbo MM. Ancient mitochondrial lineages support the prehistoric maternal root of Basques in Northern Iberian Peninsula. Eur J Hum Genet. 2017 May;25(5):631-636. doi: 10.1038/ejhg.2017.24. Epub 2017 Mar 8. PubMed PMID: 28272540; PubMed Central PMCID: PMC5437903.

  • 16: Núñez C, Baeta M, Ibarbia N, Ortueta U, Jiménez-Moreno S, Blazquez-Caeiro JL, Builes JJ, Herrera RJ, Martínez-Jarreta B, de Pancorbo MM. 17 to 23: A novel complementary mini Y-STR panel to extend the Y-STR databases from 17 to 23 markers for forensic purposes. Electrophoresis. 2017 Apr;38(7):1016-1021. doi: 10.1002/elps.201600313. Epub 2017 Jan 13. PubMed PMID: 27987217.

  • 17: Lopez-Oceja A, Gamarra D, Cardoso S, Palencia-Madrid L, Juste RA, De Pancorbo MM. Two ovine mitochondrial DNAs harboring a fifth 75/76 bp repeat motif without  altered gene expression in Northern Spain. Electrophoresis. 2017 Mar;38(6):869-875. doi: 10.1002/elps.201600308. Epub 2017 Jan 27. PubMed PMID: 27990652.

  • 18: Cardoso S, Sevillano R, Gamarra D, Santurtún A, Martínez-Jarreta B, de Pancorbo MM. Population genetic data of 38 insertion-deletion markers in six populations of the northern fringe of the Iberian Peninsula. Forensic Sci Int Genet. 2017 Mar;27:175-179. doi: 10.1016/j.fsigen.2016.12.014. Epub 2017 Jan 3. PubMed PMID: 28087155.

  • 19: Villaescusa P, Illescas MJ, Valverde L, Baeta M, Nuñez C, Martínez-Jarreta B, Zarrabeitia MT, Calafell F, de Pancorbo MM. Characterization of the Iberian Y chromosome haplogroup R-DF27 in Northern Spain. Forensic Sci Int Genet. 2017 Mar;27:142-148. doi: 10.1016/j.fsigen.2016.12.013. Epub 2016 Dec 29. PubMed PMID: 28073088.

  • 20: Gamarra D, Lopez-Oceja A, de Pancorbo MM. Genetic characterization and founder effect analysis of recently introduced Salers cattle breed population. Animal. 2017 Jan;11(1):24-32. doi: 10.1017/S1751731116001063. Epub 2016 Jun 9. PubMed PMID: 27278345.

  • 21: Setién-Olarra A, Bediaga NG, Acha-Sagredo A, Marichalar-Mendia X, de Pancorbo MM, Aguirre-Urizar JM. Genomewide miRNA profiling of oral lichenoid disorders and oral squamous cell carcinoma. Oral Dis. 2016 Nov;22(8):754-760. doi: 10.1111/odi.12536. Epub 2016 Aug 1. PubMed PMID: 27391377.

  • 22: Prieto-Fernández E, Núñez C, Baeta M, Jiménez-Moreno S, Martínez-Jarreta B, de Pancorbo MM. Forensic Spanish allele and haplotype database for a 17 X-STR panel. Forensic Sci Int Genet. 2016 Sep;24:120-123. doi: 10.1016/j.fsigen.2016.06.016. Epub 2016 Jun 22. PubMed PMID: 27388427.

  • 23: Lopez-Oceja A, Muro-Verde A, Gamarra D, Cardoso S, de Pancorbo MM. New Q lineage found in bovine (Bos taurus) of Iberian Peninsula. Mitochondrial DNA A DNA Mapp Seq Anal. 2016 Sep;27(5):3597-601. doi: 10.3109/19401736.2015.1079823. Epub 2015 Nov 11. PubMed PMID: 26554433.

  • 24: Prieto-Fernández E, Baeta M, Núñez C, Zarrabeitia MT, Herrera RJ, Builes JJ,  de Pancorbo MM. Development of a new highly efficient 17 X-STR multiplex for forensic purposes. Electrophoresis. 2016 Jul;37(12):1651-8. doi: 10.1002/elps.201500546. Epub 2016 May 2. PubMed PMID: 27060859.

  • 25: Lopez-Oceja A, Gamarra D, Borragan S, Jiménez-Moreno S, de Pancorbo MM. New cyt b gene universal primer set for forensic analysis. Forensic Sci Int Genet. 2016 Jul;23:159-165. doi: 10.1016/j.fsigen.2016.05.001. Epub 2016 May 6. PubMed PMID: 27206224.

  • 26: Bediaga NG, Beristain E, Calvo B, Viguri MA, Gutierrez-Corres B, Rezola R, Ruiz-Diaz I, Guerra I, de Pancorbo MM. Luminal B breast cancer subtype displays a dicotomic epigenetic pattern. Springerplus. 2016 May 14;5:623. doi: 10.1186/s40064-016-2235-0. eCollection 2016. PubMed PMID: 27330889; PubMed Central PMCID: PMC4870487.

  • 27: Celorrio D, Muñoz X, Amiano P, Dorronsoro M, Bujanda L, Sánchez MJ, Molina-Montes E, Navarro C, Chirlaque MD, MaríaHuerta J, Ardanaz E, Barricarte A, Rodriguez L, Duell EJ, Hijona E, Herreros-Villanueva M, Sala N, Alfonso-Sánchez MA, de Pancorbo MM. Influence of Dopaminergic System Genetic Variation and Lifestyle Factors on Excessive Alcohol Consumption. Alcohol Alcohol. 2016 May;51(3):258-67. doi: 10.1093/alcalc/agv114. Epub 2015 Oct 7. PubMed PMID: 26447226.

  • 28: Alegria-Lertxundi I, Alvarez M, Rocandio AM, de Pancorbo MM, Arroyo-Izaga M.  Nutritional Adequacy and Diet Quality in Colorectal Cancer Patients Postsurgery:  A Pilot Study. Nutr Cancer. 2016 May-Jun;68(4):577-88. doi: 10.1080/01635581.2016.1158299. Epub 2016 May 4. PubMed PMID: 27144653.

  • 29: Valverde L, Illescas MJ, Villaescusa P, Gotor AM, García A, Cardoso S, Algorta J, Catarino S, Rouault K, Férec C, Hardiman O, Zarrabeitia M, Jiménez S,  Pinheiro MF, Jarreta BM, Olofsson J, Morling N, de Pancorbo MM. New clues to the  evolutionary history of the main European paternal lineage M269: dissection of the Y-SNP S116 in Atlantic Europe and Iberia. Eur J Hum Genet. 2016 Mar;24(3):437-41. doi: 10.1038/ejhg.2015.114. Epub 2015 Jun 17. PubMed PMID: 26081640; PubMed Central PMCID: PMC4755366.

  • 30: Cardoso S, Sevillano R, Illescas MJ, de Pancorbo MM. Analysis of 16 autosomal STRs and 17 Y-STRs in an indigenous Maya population from Guatemala. Int J Legal Med. 2016 Mar;130(2):365-6. doi: 10.1007/s00414-015-1195-1. Epub 2015 May 3. PubMed PMID: 25935237.

  • 31: Figueiras A, Estany-Gestal A, Aguirre C, Ruiz B, Vidal X, Carvajal A, Salado  I, Salgado-Barreira A, Rodella L, Moretti U, Ibáñez L; EMPHOGEN group. CYP2C9 variants as a risk modifier of NSAID-related gastrointestinal bleeding: a case-control study. Pharmacogenet Genomics. 2016 Feb;26(2):66-73. doi: 10.1097/FPC.0000000000000186. PubMed PMID: 26544900; PubMed Central PMCID: PMC4704657.

  • 32: Pastor P, Moreno F, Clarimón J, Ruiz A, Combarros O, Calero M, López de Munain A, Bullido MJ, de Pancorbo MM, Carro E, Antonell A, Coto E, Ortega-Cubero  S, Hernandez I, Tárraga L, Boada M, Lleó A, Dols-Icardo O, Kulisevsky J, Vázquez-Higuera JL, Infante J, Rábano A, Fernández-Blázquez MÁ, Valentí M, Indakoetxea B, Barandiarán M, Gorostidi A, Frank-García A, Sastre I, Lorenzo E, Pastor MA, Elcoroaristizabal X, Lennarz M, Maier W, Rámirez A, Serrano-Ríos M, Lee SE, Sánchez-Juan P; Dementia Genetic Spanish Consortium (DEGESCO). MAPT H1 Haplotype is Associated with Late-Onset Alzheimer's Disease Risk in APOEɛ4 Noncarriers: Results from the Dementia Genetics Spanish Consortium. J Alzheimers  Dis. 2016;49(2):343-52. doi: 10.3233/JAD-150555. PubMed PMID: 26444794.

  • 33: Baeta M, Núñez C, Cardoso S, Palencia-Madrid L, Herrasti L, Etxeberria F, de  Pancorbo MM. Digging up the recent Spanish memory: genetic identification of human remains from mass graves of the Spanish Civil War and posterior dictatorship. Forensic Sci Int Genet. 2015 Nov;19:272-279. doi: 10.1016/j.fsigen.2015.09.001. Epub 2015 Sep 7. PubMed PMID: 26378723.

  • 34: Baeta M, Illescas MJ, García L, Núñez C, Prieto-Fernández E, Jiménez-Moreno S, de Pancorbo MM. Iberian allele frequency database for 10 X-STRs. Forensic Sci  Int Genet. 2015 Nov;19:76-78. doi: 10.1016/j.fsigen.2015.06.009. Epub 2015 Jul 2. PubMed PMID: 26164822.

  • 35: Pombar-Gomez M, Lopez-Lopez E, Martin-Guerrero I, Garcia-Orad A, de Pancorbo  MM. Erratum to: Potential relationship between single nucleotide polymorphisms used in forensic genetics and diseases or other traits in European population. Int J Legal Med. 2015 Nov;129(6):1287. doi: 10.1007/s00414-015-1227-x. PubMed PMID: 26232289.

  • 36: Bediaga NG, Aznar JM, Elcoroaristizabal X, Albóniga O, Gómez-Busto F, Artaza  Artabe I, Rocandio A, de Pancorbo MM. Associations between STR autosomal markers  and longevity. Age (Dordr). 2015 Oct;37(5):95. doi: 10.1007/s11357-015-9818-5. Epub 2015 Sep 4. PubMed PMID: 26335621; PubMed Central PMCID: PMC5005826.

  • 37: Gamarra D, Elcoroaristizabal X, Fernández-Martínez M, de Pancorbo MM. Association of the C47T Polymorphism in SOD2 with Amnestic Mild Cognitive Impairment and Alzheimer's Disease in Carriers of the APOEε4 Allele. Dis Markers. 2015;2015:746329. doi: 10.1155/2015/746329. Epub 2015 Dec 1. PubMed PMID: 26696693; PubMed Central PMCID: PMC4678069.

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